Buy Xigduo XR Online Diabetes Medication – Extended Release Dapagliflozin and Metformin for Type 2 Diabetes Management
What is Xigduo XR?
Xigduo XR extended-release pills contain both dapagliflozin and metformin. Dapagliflozin and metformin are oral diabetes medications that regulate blood sugar levels. Dapagliflozin helps the kidneys remove glucose from your bloodstream. Metformin reduces glucose synthesis in the liver and causes the intestines to absorb less glucose.
Xigduo XR is used in combination with diet and exercise to enhance blood sugar management in adults and children aged 10 and up with type 2 diabetes mellitus.
It is not intended to treat type 1 diabetes.
Xigduo XR is a prescription medication designed to help adults with Type 2 diabetes manage their blood sugar levels. This extended-release formula combines dapagliflozin, an SGLT2 inhibitor, with metformin, a trusted medication that improves insulin sensitivity. Together, these two active ingredients work to lower blood sugar by reducing glucose production in the liver, increasing the body’s use of insulin, and promoting glucose excretion through the urine. Xigduo XR is taken once daily to provide long-lasting blood sugar control.
How Xigduo XR Works for Type 2 Diabetes
Xigduo XR works through a dual mechanism: dapagliflozin blocks glucose reabsorption in the kidneys, allowing excess sugar to be eliminated through the urine, while metformin reduces the amount of sugar the liver produces and enhances insulin sensitivity. This combination helps control fasting and post-meal blood sugar levels, making Xigduo XR a powerful option for those struggling to achieve optimal glycemic control with diet and exercise alone. Its extended-release formulation ensures consistent blood sugar management throughout the day.
Xigduo XR is also used to:
lessen the chance of needing to be hospitalized for heart failure in persons with type 2 diabetes who also have heart disease.
Reduce the risk of deteriorating kidney disease, death from heart issues, and hospitalization for heart failure in persons with type 2 diabetes who also have chronic renal disease.
Xigduo was FDA-approved on October 29, 2014.
Xigduo XR side effects
Common Xigduo XR side effects affecting 5% or more people who take it include:
- female genital infections
- headache
- nausea, vomiting, diarrhea or
- runny or stuffy nose, or a sore throat.
Xigduo XR may cause some people to become dehydrated. This can make you feel dizzy, faint, lightheaded, or weak, especially while standing up (orthostatic hypotension). There have been cases of abrupt kidney injury in persons with type 2 diabetes who are taking dapagliflozin, a drug found in Xigduo XR. You may have a higher risk of dehydration if you:
- Take blood pressure medications,
- such as diuretics
- Eat a low-salt diet
- Have kidney issues
- Are 65 or older.
Consult your healthcare professional about what you can do to prevent dehydration, including how much liquids you should drink each day. Call your doctor right away if you limit the amount of food or liquid you drink, such as if you are unable to eat or if you begin to lose liquids from your body due to vomiting, diarrhea, or being in the sun for too long.
Pregnancy
Xigduo XR may affect an unborn baby’s developing kidneys and should not be used during the second or third trimester of pregnancy. If you are or become pregnant, follow your doctor’s instructions for using Xigduo XR. Blood sugar control is critical during pregnancy, and your dosage requirements may alter between trimesters.
If you become pregnant, tell your doctor straight away.
Xigduo XR contains metformin, which may accelerate ovulation in premenopausal women and raise the chance of unwanted pregnancy. Speak with your doctor about your risk.
Benefits of Xigduo XR for Blood Sugar Management
Xigduo XR offers multiple benefits for Type 2 diabetes patients. By combining the effects of dapagliflozin and metformin, it provides comprehensive blood sugar control and helps lower A1C levels. Xigduo XR may also aid in weight management, as it helps the body expel excess glucose. Additionally, the extended-release formula ensures that the medication works steadily throughout the day, reducing the risk of blood sugar spikes and crashes. Xigduo XR is also associated with cardiovascular benefits, making it an excellent choice for individuals at risk of heart disease.
How should I take Xigduo XR?
Take the Xigduo XR extended-release tablets exactly as suggested by your doctor. Follow the recommendations on your prescription label and read any drug guidelines or instruction sheets. Your doctor may occasionally adjust your dosage.
- Xigduo XR is typically taken once daily in the morning.
- Take with food to prevent stomach distress.
- Swallow the tablet whole. Avoid crushing, chewing, or breaking the extended-release tablet.You could have low blood
sugar (hypoglycemia) and feel extremely hungry, dizzy, angry, confused, worried, or shaky. To correct hypoglycemia quickly, eat or drink something with a high sugar content.
If you suffer from severe hypoglycemia, your doctor may prescribe a glucagon injection kit. Make sure your family or close friends know how to administer this injection in an emergency.
Look for indicators of high blood sugar (hyperglycemia), such as increased thirst or urine.
Stress, illness, surgery, exercise, alcohol consumption, and skipping meals all have an impact on blood sugar levels. Consult your doctor before changing your dose or drug schedule.
If you are vomiting or having diarrhea on a regular basis, or if you are sweating excessively, call your doctor. You can easily become dehydrated while taking this medication, which might result in severe low blood pressure or an electrolyte imbalance.
If you require surgery or medical tests, inform every doctor who treats you that you are taking Xigduo XR.
This medication is simply one component of a treatment plan that may include diet, exercise, weight management, blood sugar testing, and specialized medical care. Follow your doctor’s instructions closely.
Your doctor may advise you to take extra vitamin B12 while taking Xigduo XR. Only take the vitamin B12 that your doctor has prescribed.
Xigduo XR dosage
Recommended Xigduo XR dose for adults and children aged 10 and older with Type 2 diabetes to enhance blood sugar control.
Initial dose: 5 mg once daily
This is based on the dapagliflozin component. The metformin component should be tailored to the patient, and the appropriate tablet supplied.
Increase to 10 mg orally once daily (dapagliflozin component) for further glucose control if a lesser dose has been tolerated.
The maximum daily dose is dapagliflozin 10 mg combined with metformin 2000 mg.
Usual adult dose for other indications
Initial and maintenance dose: 10 mg orally once a day
This is based on the dapagliflozin component. The metformin component should be tailored to the patient, and the appropriate tablet supplied.
The maximum daily dose is dapagliflozin 10 mg combined with metformin 2000 mg.
Xigduo Ingredients
The active components are dapagliflozin and metformin hydrochloride.
Inactive components include anhydrous lactose, carboxymethylcellulose sodium, crospovidone, hypromellose, magnesium stearate, microcrystalline cellulose, and silicon dioxide.
Film coatings include polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide. FD&C Yellow No. 6/Sunset contains yellow FCF aluminum lake (Xigduo XR 5 mg/500 mg). Iron oxide (Xigduo XR 2.5 mg/1000 mg, 5 mg/1000 mg, 10 mg/500 mg, and 10 mg/1000 mg).
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